Overdispersion of the Molecular Clock Varies Between Yeast, Drosophila and Mammals

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Overdispersion of the molecular clock varies between yeast, Drosophila and mammals.

Although protein evolution can be approximated as a "molecular evolutionary clock," it is well known that sequence change departs from a clock-like Poisson expectation. Through studying the deviations from a molecular clock, insight can be gained into the forces shaping evolution at the level of proteins. Generally, substitution patterns that show greater variance than the Poisson expectation a...

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ژورنال

عنوان ژورنال: Genetics

سال: 2008

ISSN: 1943-2631

DOI: 10.1534/genetics.108.089185